Meno: | Jakub
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Priezvisko: | Havelka
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Názov: | Alignment of Nanopore Sequencing Squiggles
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Vedúci: | doc. Mgr. Tomáą Vinař, PhD.
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Rok: | 2017
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Kµúčové slová: | nanopore sequencing, dynamic time warping, alignment
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Abstrakt: | Nanopore sequencing is the latest in sequencing technologies, that is producing
long reads with hight error rates. One of the sources of these errors are
mistakes during translation from electrical signals produced to DNA sequences.
These sequences are then usually aligned to a reference sequence using common
algorithms for sequence alignment. In this thesis, we propose aligning the
electrical signals directly to the reference sequence, bypassing the translation
prone to errors.
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