Názov:Alignment of Nanopore Sequencing Squiggles
Vedúci:doc. Mgr. Tomáą Vinař, PhD.
Kµúčové slová:nanopore sequencing, dynamic time warping, alignment
Abstrakt:Nanopore sequencing is the latest in sequencing technologies, that is producing long reads with hight error rates. One of the sources of these errors are mistakes during translation from electrical signals produced to DNA sequences. These sequences are then usually aligned to a reference sequence using common algorithms for sequence alignment. In this thesis, we propose aligning the electrical signals directly to the reference sequence, bypassing the translation prone to errors.

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