Meno:Andrej
Priezvisko:Baláľ
Názov:Sequence based classification of bacteriophages
Vedúci:Mgr. Jaroslav Budią
Rok:2018
Kµúčové slová:bacteriophage, bioinformatics, host prediction
Abstrakt:Bacteriophages are viral particles that infect and replicate inside bacterial organisms. Since they are specific to a particular strain of bacteria, advances in their research could lead to novel means of targeted treatment without adverse effects on natural microbiome in patient’s body. Moreover, this treatment could be effective against bacterial strains with antibiotic resistance. We consider as one of the main bottlenecks of bacteriophage research the inability to cultivate some of the phages due to missing information about their hosts and insufficient description of their genes. We aim to address this issue with our bioinformatics pipeline which can predict bacteriophage hosts from genomic sequence and which can give us additional information about gene importance for their function.

Súbory bakalárskej práce:

scripts.zip
main.pdf