Meno: | Michaela |
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Priezvisko: | ©andalová |
Názov: | Computational Design of Probes for the Hyb-Seq Protocol |
Vedúci: | Mgr. Matúą Kempa |
Rok: | 2018 |
Kµúčové slová: | Hyb-seq, probes, phylogeny, genetic markers |
Abstrakt: | The Hyb-Seq protocol is na approach that enables finding effective genetic markers for study of phylogeny. We used an existing script – Sondovač – which is an automated pipeline that creates orthologous low-copy nuclear probes for use in plant phylogeny. Sondovač uses transcriptome and genome skim data and creates probes for later target enrichment. We created a number of initial probes from two initial sets of plant data. From these probes, we picked those we considered to be relevant genetic markers using a script we coded. The script helped to fulfill the requirements we placed on the probes and created probes that are made of 1, 000, 000 base pairs. |
Súbory bakalárskej práce:
main.pdf |
dada_script.tar.gz |
Súbory prezentácie na obhajobe: